HapMap data release #22, March 2007, on NCBI B36 assembly, dbSNP b126 -- Genotypes and frequency data for SNPs remapped to NCBI build 36 (dbSNP b126) coordinates are available in this release. A considerable number of SNPs with mapping inconsistencies from build 35 to build 36 were excluded in release #22. The excluded SNPs fall in the various categories listed below and are available in the following directory: http://www.hapmap.org/genotypes/2007-03/excluded_snps/ b36_dropped ==> SNPs with no position on B36. SNPs in this list will be included in future remappings. b36_merged ==> SNPs merged into existing refSNP clusters. In future HapMap releases, genotypes for these SNPs will have been compared with those of their new rs#, and this will be acknowledged accordingly. Lists of merged SNPs can be obtained from dbSNP, see ftp://ftp.ncbi.nih.gov/snp/organisms/human_9606/database/organism_data b36_chrom_pos_changed ==> SNPs with different chromosome positions. SNPs in this category will be included in HapMap release #22a. b36_strand_changed ==> SNPs with strand flipped in the NCBI build 36. Non-redundant QC+ SNPs: CEU JPT+CHB YRI chr1 296740 300842 295042 chr2 317542 318502 310060 chr3 246273 246742 241274 chr4 235794 236037 229979 chr5 240113 240886 234787 chr6 261164 265372 258665 chr7 206003 206785 201730 chr8 207474 211166 206488 chr9 176336 178339 175111 chr10 203991 206390 202537 chr11 198312 199751 193165 chr12 186292 187515 185020 chr13 151413 153859 150960 chr14 119915 120682 117364 chr15 104116 104725 101682 chr16 106660 106754 103910 chr17 86953 86898 84919 chr18 115675 116564 114373 chr19 54237 54387 53003 chr20 116276 116309 114079 chr21 48217 50053 48541 chr22 52986 54881 54008 chrX 106779 107709 106025 chrY 69 67 63 Total 3839330 3871213 3782785 Excluded SNPs Summary: rel21a rel22 b36_strand_change b36_chrom_pos_change b36_merged b36_dropped CEU 3904242 3839354 219 212 59647 4810 JPT+CHB 3936506 3871237 215 215 60066 4773 YRI 3846116 3782809 210 206 58196 4695